Pragmatic randomized clinical trials: best practices and statistical guidance
نویسندگان
چکیده
منابع مشابه
Good Clinical Practice Guidance and Pragmatic Clinical Trials: Balancing the Best of Both Worlds.
Randomized, clinical trials are commonly regarded as the highest level of evidence to support clinical decisions. Good Clinical Practice guidelines have been constructed to provide an ethical and scientific quality standard for trials that involve human subjects in a manner aligned with the Declaration of Helsinki. Originally designed to provide a unified standard of trial data to support submi...
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Feifang Hu*,1, Yanqing Hu2, Wei Ma3, Lixin Zhang4 & Hongjian Zhu5 Department of Statistics, George Washington University, Washington, DC 20052, USA Department of Statistics, West Virginia University, Morgantown, WV 26506, USA Biogen Idec, 14 Cambridge Center, Cambridge, MA 02142, USA Department of Mathematics, Zhejiang University, Hangzhou 310006, PR China Department of Biostatistics, The Unive...
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Cluster randomized controlled trials (cRCTs; also known as group randomized trials and community-randomized trials) are multilevel experiments in which units that are randomly assigned to experimental conditions are sets of grouped individuals, whereas outcomes are recorded at the individual level. In human cRCTs, clusters that are randomly assigned are typically families, classrooms, schools, ...
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ژورنال
عنوان ژورنال: Health Services and Outcomes Research Methodology
سال: 2018
ISSN: 1387-3741,1572-9400
DOI: 10.1007/s10742-018-0192-5